IgA nephropathy associated with X-linked thrombocytopenia.

2004 JUN 10 - (NewsRx.com & NewsRx.net) -- IgA nephropathy is associated with X-linked thrombocytopenia.

According to recent research from Japan, "X-Linked thrombocytopenia (XLT) is characterized by congenital thrombocytopenia with small platelets and absence of immunodeficiency; XLT is an allelic variant of Wiskott-Aldrich syndrome (WAS). Both entities are caused by mutations in the same gene. This study presents the case of an 8-year-old boy with XLT. He developed immunoglobulin A (IgA) nephropathy at the age of 4 years."

"Genetic analysis confirmed the XLT diagnosis," said Hiro Matsukura and colleagues at Saiseikai Toyama Hospital. "His maternal uncle …